TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of human Biotin-DMRPEIWIAQELRRIGDEFNAYYARR peptide binding to 6XHis-tagged human MCl-1 (171 to 327 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and biotinylated Bim BH3 peptide interaction usi...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 0.0760nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Binding affinity to Mcl-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition of human Biotin-DMRPEIWIAQELRRIGDEFNAYYARR peptide binding to Bcl-xL (unknown origin) after 120 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition of recombinant His6-tagged human Bcl-xL (1 to 196 residues) expressed in Escherichia coli using biotinylated Bim BH3 peptide as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Inhibition of recombinant His10-tagged human Bcl-2 (2 to 211 residues) using biotinylated Bim BH3 peptide as substrate incubated for 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Inhibition of human Biotin-DMRPEIWIAQELRRIGDEFNAYYARR peptide binding to recombinant 10His-tagged human Bcl2 (2 to 211 residues) expressed in Escheri...More data for this Ligand-Target Pair