TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0470nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0840nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0880nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0940nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.5nMAssay Description:Inhibition of MPS1 (510 to 857 residues) catalytic domain (unknown origin) expressed in Escherichia coli after 15 mins by mass-spectrometry analysisMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.5nMAssay Description:Inhibition of MPS1 (510 to 857 residues) catalytic domain (unknown origin) expressed in Escherichia coli after 15 mins by mass-spectrometry analysisMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Competitive inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate by Lineweaver-Burk plot analysis in prese...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.770nMAssay Description:Competitive inhibition of TTK (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.820nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.830nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused MPS1 (1 to 857 residues) using histone H3 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 14.2nMAssay Description:Covalent inhibition of human full length N-terminal GST-fused MPS1 (1 to 857 residues) assessed as inhibition constant by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 5.40E+3nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 2.48E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 2.56E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3.01E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3.02E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 8.08E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 9.12E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 9.47E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: 9.81E+4nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair