Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of kd for monomerid = 50103596
TargetFlavin reductase (NADPH)(Homo sapiens)
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50103596((E)-2-hydroxy-5-((4-(N-pyridin-2-ylsulfamoyl)-phen...)
Affinity DataKd:  437nMAssay Description:Binding affinity to human N-terminal His6-tagged and thrombin cleavage fused BLVRB expressed in Escherichia coli BL21 (DE3) assessed as dissociation ...More data for this Ligand-Target Pair
TargetFlavin reductase (NADPH)(Homo sapiens)
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50103596((E)-2-hydroxy-5-((4-(N-pyridin-2-ylsulfamoyl)-phen...)
Affinity DataKd:  440nMAssay Description:Binding affinity to human N-terminal His6-tagged and thrombin cleavage fused BLVRB expressed in Escherichia coli BL21 (DE3) assessed as dissociation ...More data for this Ligand-Target Pair
TargetFlavin reductase (NADPH)(Homo sapiens)
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50103596((E)-2-hydroxy-5-((4-(N-pyridin-2-ylsulfamoyl)-phen...)
Affinity DataKd:  440nMAssay Description:An enzyme activity assay for BLVRB was conducted. Since BLVRB catalyzes the NAD(P)H dependent readuction of FMN, changes in the NAD(P)H concentration...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50103596((E)-2-hydroxy-5-((4-(N-pyridin-2-ylsulfamoyl)-phen...)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

LigandPNGBDBM50103596((E)-2-hydroxy-5-((4-(N-pyridin-2-ylsulfamoyl)-phen...)
Affinity DataKd:  9.00E+3nMpH: 7.0Assay Description:Surface plasmon resonance (SPR) assays were carried out on a BIAcore 3000 instrument (Biacore, Inc). Briefly, purified hTNFα was dissolved at 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed