Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50001352
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014955(4-Hydroxy-6-[2-(2,4,7-trichloro-naphthalen-1-yl)-e...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014949(4-Hydroxy-6-[2-(2,4,6-trichloro-naphthalen-1-yl)-e...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014956(6-[2-(4,7-Dichloro-2-methyl-naphthalen-1-yl)-ethyl...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014954(6-[2-(2,7-Dichloro-4-methyl-naphthalen-1-yl)-ethyl...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014948(6-[2-(7-Chloro-2,4-dimethyl-naphthalen-1-yl)-ethyl...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014957(4-Hydroxy-6-[2-(2,4,7-trimethyl-naphthalen-1-yl)-e...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014950(6-[2-(2-Chloro-naphthalen-1-yl)-vinyl]-4-hydroxy-t...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014947(6-[2-(4-Bromo-naphthalen-1-yl)-vinyl]-4-hydroxy-te...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014958(6-[2-(8-Bromo-naphthalen-1-yl)-vinyl]-4-hydroxy-te...)
Affinity DataIC50:  4.12E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014953(6-[2-(4,6-Dichloro-naphthalen-1-yl)-ethyl]-4-hydro...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014951(6-[2-(4-Bromo-naphthalen-1-yl)-ethyl]-4-hydroxy-te...)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014952(4-Hydroxy-6-(2-naphthalen-1-yl-ethyl)-tetrahydro-p...)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed