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Found 28 Enz. Inhib. hit(s) with all data for entry = 50007863
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068752(8-Methyl-2-(4-nitro-phenyl)-3H-quinazolin-4-one | ...)
Affinity DataIC50:  130nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068762(2-(4-Methoxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)
Affinity DataIC50:  190nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068755(2-(4-Hydroxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)
Affinity DataIC50:  220nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068764(8-Hydroxy-2-(4-nitro-phenyl)-3H-quinazolin-4-one |...)
Affinity DataIC50:  230nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068760(4-(8-Methyl-4-oxo-3,4-dihydro-quinazolin-2-yl)-ben...)
Affinity DataIC50:  270nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068770(8-Hydroxy-2-(4-hydroxy-phenyl)-3H-quinazolin-4-one...)
Affinity DataIC50:  290nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068753(2-(4-Amino-phenyl)-8-methoxy-3H-quinazolin-4-one |...)
Affinity DataIC50: >300nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068761(2,8-Dimethyl-3H-quinazolin-4-one | CHEMBL151549)
Affinity DataIC50:  390nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068774(8-HYDROXY-2-METHYL-3-HYDRO-QUINAZOLIN-4-ONE | 8-Hy...)
Affinity DataIC50:  400nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM27682(5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...)
Affinity DataIC50:  440nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068766(2-(4-Amino-phenyl)-8-methyl-3H-quinazolin-4-one | ...)
Affinity DataIC50:  440nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068771(2-(4-Amino-phenyl)-8-hydroxy-3H-quinazolin-4-one |...)
Affinity DataIC50:  520nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068772(8-Methoxy-2-methyl-3H-quinazolin-4-one | CHEMBL435...)
Affinity DataIC50:  780nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068754(8-Methoxy-2-(4-nitro-phenyl)-3H-quinazolin-4-one |...)
Affinity DataIC50:  850nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)
Affinity DataIC50:  870nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068751(8-Hydroxy-2-phenyl-3H-quinazolin-4-one | CHEMBL341...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068768(4-(8-Methoxy-4-oxo-3,4-dihydro-quinazolin-2-yl)-be...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068763(2-(4-Azido-phenyl)-8-methoxy-3H-quinazolin-4-one |...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068776(8-Methoxy-2-(4-methoxy-phenyl)-3H-quinazolin-4-one...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068767(8-Methoxy-2-phenyl-3H-quinazolin-4-one | CHEMBL126...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068756(4-(8-Methyl-4-oxo-3,4-dihydro-quinazolin-2-yl)-ben...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068769(3-Hydroxy-benzamide | 3-hydroxybenzamide | CHEMBL4...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068765(8-Methyl-2-(4-trifluoromethyl-phenyl)-3H-quinazoli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068775(2H-Isoquinolin-1-one | CHEMBL339695 | isoquinolin-...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM27506(3-AB | 3-aminobenzamide | CHEMBL81977)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068759(8-Methoxy-2-(4-trifluoromethyl-phenyl)-3H-quinazol...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068773(8-Hydroxy-2,3-dimethyl-3H-quinazolin-4-one | CHEMB...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068757(8-Methoxy-2,3-dimethyl-3H-quinazolin-4-one | CHEMB...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed