TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.630nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.860nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.860nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK in human peripheral B cells assessed as reduction in anti-IgM/IgG-induced CD86 surface expressionMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of BTK in human PBMC cells assessed as inhibition of FCepsilonR1/immune complex-induced TNFalpha productionMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of BTK in human PBMC cells assessed as inhibition of FCepsilonR1/immune complex-induced TNFalpha productionMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of FGR (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of YES1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of BTK in human peripheral B cells assessed as reduction in anti-IgM/IgG-induced CD86 surface expressionMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in FCepsilonR1/anti-IgE-induced CD63 surface expression on basophilsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in goat anti human IgM/human IL4-stimulated CD69 cell surface expression on peripheral B...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in goat anti human IgM/human IL4-stimulated CD69 cell surface expression on peripheral B...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in goat anti human IgM/human IL4-stimulated CD69 cell surface expression on peripheral B...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in goat anti human IgM/human IL4-stimulated CD69 cell surface expression on peripheral B...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in goat anti human IgM/human IL4-stimulated CD69 cell surface expression on peripheral B...More data for this Ligand-Target Pair