TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H](+)-[3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]-unlike-ifenprodil from recombinant human GluN2B expressed in L-M(TK-) cell membranes by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 7.80nMAssay Description:Displacement of [3H]-unlike-ifenprodil from recombinant human GluN2B expressed in L-M(TK-) cell membranes by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 8.60nMAssay Description:Displacement of [3H](+)-[3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-unlike-ifenprodil from recombinant human GluN2B expressed in L-M(TK-) cell membranes by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-unlike-ifenprodil from recombinant human GluN2B expressed in L-M(TK-) cell membranes by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H](+)-[3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [3H]prazosin from alpha-1A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 46nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Displacement of [3H](+)-[3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 75nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [3H]prazosin from alpha-1A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 278nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 338nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 369nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 370nMAssay Description:Displacement of [3H]prazosin from alpha-1A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 421nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 513nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7B receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 530nMAssay Description:Displacement of [3H]prazosin from alpha-1A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 708nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 748nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Displacement of [3H]RX821002 from alpha-2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]RX821002 from alpha-2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 5.50E+3nMAssay Description:Displacement of [3H]RX821002 from alpha-2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 6.10E+3nMAssay Description:Displacement of [3H]RX821002 from alpha-2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7B receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7B receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7B receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin) incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human GluN2B expressed in Xenopus laevis oocytes assessed as reduction in glutamate and glycine stimulated ion flux by two-ele...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Antagonist activity at human GluN2B expressed in Xenopus laevis oocytes assessed as reduction in glutamate and glycine stimulated ion flux by two-ele...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataIC50: 525nMAssay Description:Antagonist activity at human GluN2B expressed in Xenopus laevis oocytes assessed as reduction in glutamate and glycine stimulated ion flux by two-ele...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataIC50: 698nMAssay Description:Antagonist activity at human GluN2B expressed in Xenopus laevis oocytes assessed as reduction in glutamate and glycine stimulated ion flux by two-ele...More data for this Ligand-Target Pair
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