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Found 41 Enz. Inhib. hit(s) with all data for entry = 50012421
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557532(CHEMBL4792421)
Affinity DataKi:  0.0820nMAssay Description:Competitive inhibition of Electrophorus electricus AChE using varying levels of acetylthiocholine iodide as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557533(CHEMBL4757683)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557532(CHEMBL4792421)
Affinity DataIC50:  0.0920nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557531(CHEMBL4778167)
Affinity DataIC50:  0.307nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557533(CHEMBL4757683)
Affinity DataIC50:  0.338nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557530(CHEMBL4761887)
Affinity DataIC50:  0.383nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557532(CHEMBL4792421)
Affinity DataIC50:  0.616nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557531(CHEMBL4778167)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557530(CHEMBL4761887)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant human MAOA using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557523(CHEMBL4778409)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557523(CHEMBL4778409)
Affinity DataIC50:  12nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557519(CHEMBL4780953)
Affinity DataIC50:  26nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557520(CHEMBL4788648)
Affinity DataIC50:  31nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557536(CHEMBL4754258)
Affinity DataIC50:  33nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557522(CHEMBL4780148)
Affinity DataIC50:  50nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557522(CHEMBL4780148)
Affinity DataIC50:  66nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557518(CHEMBL4746533)
Affinity DataIC50:  72nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557521(CHEMBL4762169)
Affinity DataIC50:  660nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50:  830nMAssay Description:Inhibition of recombinant human MAOA using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557535(CHEMBL4765003)
Affinity DataIC50:  960nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557538(CHEMBL4786674)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557534(CHEMBL4752902)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557525(CHEMBL4750877)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557526(CHEMBL4779785)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  4.56E+3nMAssay Description:Inhibition of recombinant human MAOA using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557532(CHEMBL4792421)
Affinity DataIC50:  5.88E+3nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557537(CHEMBL4798284)
Affinity DataIC50:  8.26E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  8.57E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557527(CHEMBL4740443)
Affinity DataIC50:  8.86E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557524(CHEMBL4782916)
Affinity DataIC50:  9.68E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557529(CHEMBL4749366)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50557528(CHEMBL4791232)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed