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Found 8 Enz. Inhib. hit(s) with all data for entry = 50015189
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583557(CHEMBL5075993)
Affinity DataKi:  665nMAssay Description:Binding affinity to DENV NS2B-NS3 protease assessed as inhibition constant using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate incubated for 60 min by mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583556(CHEMBL5083861)
Affinity DataKi:  7.25E+3nMAssay Description:Binding affinity to DENV NS2B-NS3 protease assessed as inhibition constant using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate incubated for 60 min by mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583557(CHEMBL5075993)
Affinity DataIC50:  6nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583558(CHEMBL5075008)
Affinity DataIC50:  9nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583559(CHEMBL5092085)
Affinity DataIC50:  12nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583560(CHEMBL5081752)
Affinity DataIC50:  74nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583556(CHEMBL5083861)
Affinity DataIC50:  500nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease expressed in Escherichia coli assessed as fluorescence emission using Bz-nKRR-AMC as substrate by microplate re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583556(CHEMBL5083861)
Affinity DataIC50:  500nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed