Found 17 Enz. Inhib. hit(s) with all data for entry = 50017060 TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human Dyrk1AMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human Dyrk1AMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Dyrk1B (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 159nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 177nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of DYRK1A in human HeLa cells transiently expressing GFP-SF3B1 fusion protein assessed as reduction in SF3B1 phosphorylation incubated for...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of Dyrk1B (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Dyrk2 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Dyrk2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of alpha-syn (unknown origin) aggregation assessed as reduction in fluorescence intensity measured after 24 hrs by ThT flourescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of alpha-syn (unknown origin) aggregation assessed as reduction in fluorescence intensity measured after 24 hrs by ThT flourescence assayMore data for this Ligand-Target Pair
