Compile Data Set for Download or QSAR
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Found 13 Enz. Inhib. hit(s) with all data for entry = 50017980
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606675(CHEMBL3219079)
Affinity DataKi:  0.900nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606676(CHEMBL3219087)
Affinity DataKi:  1nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606674(CHEMBL3219103)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606673(CHEMBL3219100)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606672(CHEMBL3219101)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606671(CHEMBL3219102)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606668(CHEMBL5220314)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human ACE2 using 7-Mca-YVADAPK (Dnp) as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606669(CHEMBL5220968)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant human ACE2 using 7-Mca-YVADAPK (Dnp) as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM21489((2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of recombinant human ACE2 using 7-Mca-YVADAPK (Dnp) as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM21489((2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human ACE using Mca-RPGFSAFK (Dnp)- OH as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606669(CHEMBL5220968)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of recombinant human ACE using Mca-RPGFSAFK (Dnp)- OH as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606668(CHEMBL5220314)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of recombinant human ACE using Mca-RPGFSAFK (Dnp)- OH as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606670(CHEMBL3219078)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of recombinant human ACE2 using fluorogenic peptide substrate VI measured every 36 sec for 10 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed