Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50018510
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50:  6nMAssay Description:Inhibition of human wild type DYRK1A (M1 to S629) expressed in bacterial system by Ambit Kinomescan binding assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50:  6nMAssay Description:Inhibition of human DYRK1A at 3 uM in presence of ATPMore data for this Ligand-Target Pair
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LigandPNGBDBM50538083(CHEMBL4638292)
Affinity DataIC50:  6nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50375654(CHEMBL99203 | US11633415, Compound 5-iodotubercidi...)
Affinity DataIC50:  13nMAssay Description:Inhibition of DYRK1A (unknown origin) in presence of ATP at 15 uMMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50538083(CHEMBL4638292)
Affinity DataIC50:  16nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
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LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50:  27nMAssay Description:Inhibition of DYRK1A (unknown origin) at 10 uM by ADP hunter plus assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50:  40nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50538085(CHEMBL4634969)
Affinity DataIC50:  43nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50571728(CHEMBL4855547)
Affinity DataIC50:  89nMAssay Description:Inhibition of human DYRK1A by Eu kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50538083(CHEMBL4638292)
Affinity DataIC50:  100nMAssay Description:Inhibition of human wild type DYRK1A (M1 to S629) expressed in bacterial system by Ambit Kinomescan binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50: <100nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50367664(CHEMBL4066450)
Affinity DataIC50: >8.30E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50466133(CHEMBL4292847 | US11547712, Compound 3-1)
Affinity DataIC50:  9.41E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) at 1 uM by kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50466137(CHEMBL4280328 | US11547712, Compound 3-15)
Affinity DataKd:  71nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant at 3 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50466133(CHEMBL4292847 | US11547712, Compound 3-1)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50466133(CHEMBL4292847 | US11547712, Compound 3-1)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50466136(CHEMBL4292463 | US11547712, Compound 3-12)
Affinity DataKd:  185nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant at 3 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed