Affinity DataKi: 44nMAssay Description:Binding affinity to LCK (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 0.270nMAssay Description:Inhibition of PI3Kdelta (unknown origin) at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: <0.300nMAssay Description:Inhibition of human recombinant FGFR3More data for this Ligand-Target Pair
Affinity DataIC50: <0.300nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type BTK (unknown origin) in presence of 1 uM ATP by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human recombinant FGFR2 in the presence of ATP at 0.8 uM measured after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3Kdelta (unknown origin) at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of EGFR T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant FGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant FGFR2 expressed in Escherichia coli BL21 DE3 assessed as inhibition by western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant FGFR4More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant FGFR3 expressed in Escherichia coli BL21 DE3 assessed as inhibition by western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of EGFR T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of EGFR T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Src kinase (unknown origin) phosphorylation at Tyr416/419 residues incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of His-tagged LCK (62 to 509 residues) (unknown origin) expressed in Sf9 insect cells at 10 uM using poly (Glu, Tyr) 4:1 as substrate incu...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant FGFR1 expressed in Escherichia coli BL21 DE3 assessed as inhibition by western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of recombinant wild type FGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant GST-tagged RET (unknown origin) using EAIYAAPFKKK as substrate in the presence of ATP of 100 uM by western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of FYN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of FYN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Src kinase (unknown origin) phosphorylation at Tyr416/419 residues incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of recombinant BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human recombinant FGFR4 expressed in Escherichia coli BL21 DE3 assessed as inhibition by western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of LYN (unknown origin) at 1 uM by kinase-profiling analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Src kinase (unknown origin) phosphorylation at Tyr416/419 residues incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 9.70nMAssay Description:Inhibition of PI3Kdelta (unknown origin) at 1 uMMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kdelta (unknown origin) at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of IGF-1R (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant FGFR1 in the presence of ATP at 0.16 uM measured after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant FGFR3 in the presence of ATP at 0.8 uM measured after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Src kinase (unknown origin) phosphorylation at Tyr416/419 residues incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of HER3 (unknown origin)More data for this Ligand-Target Pair
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