Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 50018842
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  8nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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LigandPNGBDBM50613105(CHEMBL5271811)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50613104(CHEMBL5268463)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50613103(CHEMBL5269847)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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LigandPNGBDBM50613100(CHEMBL5275604)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: <10nMAssay Description:Inhibition of Pseudomonas aeruginosa DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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LigandPNGBDBM50568726(CHEMBL4854181)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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LigandPNGBDBM50613107(CHEMBL5267594)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50613106(CHEMBL5276709)
Affinity DataIC50:  13nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50613101(CHEMBL5282927)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50613102(CHEMBL5285251)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha relaxationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed