Affinity DataKi: 12nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibition of constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human EGFR L858R mutant (669 to 1210 residues) expressed in Sf21 insect cells using 5-FAM-EEPLYWSFPAKKK-CONH2 as substrate incubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged human CDK2/Cyclin A2 expressed in baculovirus infected Sf9 cells using 5-FAM-QSPKKG-CONH2 as substrate incubated for 60 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of C-terminal His6 tagged human full length CDK1/N-terminal GST-tagged human full length Cyclin B expressed in baculovirus infected Sf21 c...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal His6 tagged full length recombinant human CDK9/full length human Cyclin T1 expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of full length human CDK4/N-terminal GST fused human cyclinD3 expressed in baculovirus expression system using 5-FAMIPTSPITTTYFFFKKK-COOH ...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant full length human C-terminal His6-tagged CDK7/untagged recombinant full length human Cyclin H/N-terminal GST-tagged recombi...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-tagged full length human BTK (2 to 659 residues) expressed in Sf21 insect cells using 5-FAM-EAIYAAPFAKKK as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 133nMAssay Description:Inhibition of full length human CDK6/N-terminal GST fused human cyclinD3 expressed in baculovirus expression system using 5-FAMIPTSPITTTYFFFKKK-COOH ...More data for this Ligand-Target Pair