Compile Data Set for Download or QSAR
maximum 50k data
Found 155 Enz. Inhib. hit(s) with all data for entry = 50036411
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048739((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048774((R)-2-{[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlo...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048724((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048725((R)-3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048726((R)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048781((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048787((R)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048777((S)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048797(2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048738(3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048748((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048780((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048742((R)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048788((S)-3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048739((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  20nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048767((S)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048783((R)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048758((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048743((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048751((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048790((S)-3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048734((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048770((R)-3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048775((R)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048745((S)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048735((R)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  36nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048773((R)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  37nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048776((S)-5-(8-Aza-spiro[4.5]dec-8-yl)-4-[5-(8-aza-spiro...)
Affinity DataIC50:  37nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048756((R)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048790((S)-3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  39nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048726((R)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  40nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048746((S)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048777((S)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  44nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048738(3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50:  45nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048724((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  46nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048737((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048725((R)-3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  49nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048744((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048797(2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50:  49nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048766((S)-2-{[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlo...)
Affinity DataIC50:  51nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048793(2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50:  51nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048782(2-{[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-b...)
Affinity DataIC50:  54nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048728((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  54nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048747(2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048750((S)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048741(2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048774((R)-2-{[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlo...)
Affinity DataIC50:  57nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048780((S)-4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  57nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048765((S)-3-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  57nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048767((S)-2-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichlor...)
Affinity DataIC50:  61nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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