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Found 2 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50559939'
LigandPNGBDBM50559939(CHEMBL4756373)
Affinity DataEC50:  132nMAssay Description:Induction of HMGCR degradation in HEK293 cells incubated for 4 hrs by luciferase based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50559939(CHEMBL4756373)
Affinity DataEC50:  153nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed