Report error Found 10 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50151982'
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 9.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]8-OH-DAPT from 5-HT1A receptor in human HEK293 cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of 5-HT1a (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Agonist activity at human 5HT1A expressed in CHO cell membranes assessed as increase in [35S]-GTPgammaS binding after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expresssed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells after 60 mins by Eu-cAMP solution based ultra LANCE assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataEC50: 0.790nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human 5H1A receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair