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Found 8 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50305261'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataKi:  26nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataKi:  26nMAssay Description:Binding affinity to human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataKi:  34nMAssay Description:Binding affinity to human recombinant 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataKi:  34nMAssay Description:Binding affinity to 5-HT6R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(RAT)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataKi:  119nMAssay Description:Binding affinity to rat recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataIC50:  890nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production by LANCE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataIC50:  890nMAssay Description:Antagonist activity at human recombinant 5-HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced intracellular cAMP accu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataIC50:  1.16E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed