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Found
1
Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor [L1196M]' and Ligand = 'BDBM261649'
Target
ALK tyrosine kinase receptor [L1196M]
(Homo sapiens (Human))
UniversitÁ
US Patent
Ligand
BDBM261649
(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
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Affinity Data
IC50: 44.6nM
pH: 7.5 T: 2°C
Assay Description:
GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...
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Target Info
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UniProtKB/SwissProt
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Ligand Info
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US Patent
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