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Found 2 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50249648'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50249648(CHEMBL523281 | Dimethyl-(8-phenyl-2,3,5,6-tetrahyd...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Mus musculus (Mouse))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50249648(CHEMBL523281 | Dimethyl-(8-phenyl-2,3,5,6-tetrahyd...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of verapamil-stimulated ATPase activity of mouse cysteine-less MDR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed