Found 2 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50423653'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University of New York
Curated by ChEMBL
The State University of New York
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of P-gp (unknown origin)More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University of New York
Curated by ChEMBL
The State University of New York
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...More data for this Ligand-Target Pair