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Found 3 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM202363'
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)
Affinity DataIC50:  3.60nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universitat De Barcelona

US Patent
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)
Affinity DataIC50:  32.6nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent