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Found 3 Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 1' and Ligand = 'BDBM50010268'
TargetAdenylate cyclase type 1(Homo sapiens (Human))
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010268((2-Amino-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,10...)
Affinity DataIC50:  128nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Homo sapiens (Human))
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010268((2-Amino-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,10...)
Affinity DataEC50:  700nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010268((2-Amino-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,10...)
Affinity DataKd:  98nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed