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Found 3 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] B' and Ligand = 'BDBM86779'
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

LigandPNGBDBM86779(Phthalonitrile analogue, 4h)
Affinity DataIC50:  4.80nMpH: 7.4 T: 2°CAssay Description:MAO inhibition potencies of phthalonitrile, benzonitrile and benzyl phenyl ether analogs, recombinant human MAO-A and -B were employed as enzyme sour...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

LigandPNGBDBM86779(Phthalonitrile analogue, 4h)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant MAOB expressed in insect cell microsomes using kynuramine as substrate after 20 mins by fluorescence spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

LigandPNGBDBM86779(Phthalonitrile analogue, 4h)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant MAO-B assessed as kynuramine oxidation to 4-hydroxyquinoline formation by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed