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Found 4 Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM468334'
TargetAndrogen receptor(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468334(US10806720, Compound 1015 | US11230523, Compound 1...)
Affinity DataKi: >1.00E+4nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468334(US10806720, Compound 1015 | US11230523, Compound 1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468334(US10806720, Compound 1015 | US11230523, Compound 1...)
Affinity DataIC50:  1.07E+3nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468334(US10806720, Compound 1015 | US11230523, Compound 1...)
Affinity DataIC50:  1.74E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent