Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50156508'
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156508((1S,6R,7S)-4-(4-Cyano-naphthalen-1-yl)-3,5-dioxo-2...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-DHT from androgen receptor of human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156508((1S,6R,7S)-4-(4-Cyano-naphthalen-1-yl)-3,5-dioxo-2...)
Affinity DataIC50:  580nMAssay Description:In vitro antagonistic activity against androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156508((1S,6R,7S)-4-(4-Cyano-naphthalen-1-yl)-3,5-dioxo-2...)
Affinity DataIC50:  1.87E+3nMAssay Description:In vitro antagonistic activity against mutant androgen receptor of LNCap cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed