Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50157816'
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157816((2R,6S)-4-(3,4-Dichloro-phenyl)-4-aza-tricyclo[5.2...)
Affinity DataKi:  6nMAssay Description:Binding affinity for mutant T877A Androgen receptor in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157816((2R,6S)-4-(3,4-Dichloro-phenyl)-4-aza-tricyclo[5.2...)
Affinity DataKi:  158nMAssay Description:Binding affinity for androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157816((2R,6S)-4-(3,4-Dichloro-phenyl)-4-aza-tricyclo[5.2...)
Affinity DataIC50:  41nMAssay Description:Inhibition of mutant T877A Androgen receptor in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157816((2R,6S)-4-(3,4-Dichloro-phenyl)-4-aza-tricyclo[5.2...)
Affinity DataIC50:  180nMAssay Description:Inhibition of androgen dependent human prostate cancer cell MDA-MB-PCa2b proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157816((2R,6S)-4-(3,4-Dichloro-phenyl)-4-aza-tricyclo[5.2...)
Affinity DataIC50:  307nMAssay Description:Inhibition of androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed