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Found 3 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50254585'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254585(1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50:  30nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254585(1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254585(1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50:  100nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 26 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed