Found 6 Enz. Inhib. hit(s) with Target = 'Atrial natriuretic peptide receptor 3' and Ligand = 'BDBM50604565' TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 8.64E+3nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 860nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKd: 1.46E+5nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+4nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 1.55E+4nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
