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Found 5 Enz. Inhib. hit(s) with Target = 'Atypical chemokine receptor 3' and Ligand = 'BDBM50542061'
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataKi:  597nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataKi:  603nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50:  622nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50:  631nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed