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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM26320'
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26320(1-phenyl-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino...)
Affinity DataIC50:  52nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26320(1-phenyl-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino...)
Affinity DataIC50:  52nMAssay Description:Inhibition of aurora A kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26320(1-phenyl-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Aurora A after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed