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Found 3 Enz. Inhib. hit(s) with Target = 'B-cell lymphoma 6 protein' and Ligand = 'BDBM50597104'
TargetB-cell lymphoma 6 protein(Homo sapiens)
Cancer Research Technology

US Patent
LigandPNGBDBM50597104(CHEMBL5173975 | US20230287003, Example 1e)
Affinity DataIC50:  851nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained 1 nM Trx-6×His-BCL6 (in house-produced, human BCL6 BTB domain c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetB-cell lymphoma 6 protein(Homo sapiens)
Cancer Research Technology

US Patent
LigandPNGBDBM50597104(CHEMBL5173975 | US20230287003, Example 1e)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human N-terminal thioredoxin 6-His tagged BCL6 BTB domain (5 to 129 residues) expressed in Escherichia coli BL21-AI using BCOR-AF633 pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetB-cell lymphoma 6 protein(Homo sapiens)
Cancer Research Technology

US Patent
LigandPNGBDBM50597104(CHEMBL5173975 | US20230287003, Example 1e)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human C-terminal nanoLuc-tagged BCL6 expressed in HEK293T cells co-expressing HaloTagged-SMRT using NanoBRET furimazine as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed