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Report error Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM190714'
TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM190714(US9181236, 18)
Affinity DataKi:  2.70nM ΔG°:  -49.7kJ/molepH: 5.0 T: 30°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In DepthDetails US Patent