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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM477923'
Target
Beta-secretase 1
(Homo sapiens (Human))
Amgen
US Patent
Ligand
BDBM477923
((1S,5S,6S)-3-amino-5-(5-((5-cyano-3-methylpyridin-...)
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Affinity Data
IC50: 21nM
Assay Description:
The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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