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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1 [1-454]' and Ligand = 'BDBM150712'
Target
Beta-secretase 1 [1-454]
(Homo sapiens (Human))
Vitae Pharmaceutical
US Patent
Ligand
BDBM150712
(US8981112, 19 | US9526727, 19 | US9949975, Example...)
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Affinity Data
IC50: 6nM
pH: 4.4
Assay Description:
The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...
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Target Info
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Ligand Info
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US Patent
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