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1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM365582'
Target
Beta-secretase 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM365582
(US9868738, Example 18)
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Affinity Data
Ki: 39.8nM
Assay Description:
Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...
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Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
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Details
US Patent
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