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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM372697'
TargetBeta-secretase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM372697((1S,5S,6S)-5-(5-((E)-2-(5-chloropyridin-2-yl)-2-fl...)
Affinity DataIC50:  281nMAssay Description:Inhibition of recombinant human BACE2 using fluorescence substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM372697((1S,5S,6S)-5-(5-((E)-2-(5-chloropyridin-2-yl)-2-fl...)
Affinity DataIC50:  281nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent