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Found 4 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50210977'
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210977((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210977((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...)
Affinity DataIC50:  7nMAssay Description:Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210977((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Mus musculus)
Tanabe Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210977((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...)
Affinity DataIC50:  260nMAssay Description:Binding affinity at mouse CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed