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Found 2 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 4' and Ligand = 'BDBM50565501'
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50565501(CHEMBL4783831)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity at CXCR4 in human CD4-positive T cells assessed as inhibition of CXCL12-induced cytosolic calcium flux preincubated for 20 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50565501(CHEMBL4783831)
Affinity DataIC50:  220nMAssay Description:Inhibition of APC-conjugated anti-human CXCR4 clone 12G5 binding to CXCR4 in human HPBALL cells measured after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed