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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50315404'
LigandPNGBDBM50315404((4'S)-3'-methyl-2-((4-oxo-2a,3,4,5-tetrahydropyrro...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315404((4'S)-3'-methyl-2-((4-oxo-2a,3,4,5-tetrahydropyrro...)
Affinity DataIC50:  7.30nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315404((4'S)-3'-methyl-2-((4-oxo-2a,3,4,5-tetrahydropyrro...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed