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Found 3 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM35871'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM35871(5,6-di-p-tolyl-pyrazine-2-carboxylic acid piperidi...)
Affinity DataKi:  53nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM35871(5,6-di-p-tolyl-pyrazine-2-carboxylic acid piperidi...)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM35871(5,6-di-p-tolyl-pyrazine-2-carboxylic acid piperidi...)
Affinity DataIC50:  12.0nMAssay Description:Antagonist activity against human recombinant cannabinoid-1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed