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Found 3 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM50432712'
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432712(AM4089 | CHEMBL2348473)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432712(AM4089 | CHEMBL2348473)
Affinity DataEC50:  450nMAssay Description:Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432712(AM4089 | CHEMBL2348473)
Affinity DataEC50:  8nMAssay Description:Partial agonist activity at human CB1 receptor transfected in HEK293 cells assessed as reduction in forskolin-stimulated cAMP accumulation after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed