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Found 2 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM50321257'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50321257(5-hydroxy-1-tosyl-1H-pyrrol-2(5H)-one | CA inhibit...)
Affinity DataKi:  510nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50321257(5-hydroxy-1-tosyl-1H-pyrrol-2(5H)-one | CA inhibit...)
Affinity DataKi:  584nM ΔG°:  -35.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed