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Found 11 Enz. Inhib. hit(s) with Target = 'Casein kinase II subunit alpha 3' and Ligand = 'BDBM50335638'
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  5.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  5.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair