Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Caspase-1' and Ligand = 'BDBM50200553'
TargetCaspase-1(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200553(CHEMBL3898379)
Affinity DataKi:  48nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200553(CHEMBL3898379)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant DTT-activated caspase-1 expressed in Escherichia coli using WEHD-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200553(CHEMBL3898379)
Affinity DataIC50:  167nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed