Affinity DataKi: 11nMAssay Description:Enzyme activities with or without inhibitors were measured using a fluorescence assay. The formation of the cleavage product AFC was monitored for 90...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Evaluated for the dissociation constant for the inhibition of caspase-3More data for this Ligand-Target Pair
Affinity DataKi: 56.1nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
Affinity DataIC50: 119nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of caspase 3 in neutrophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.67E+3nMAssay Description:Inhibition of staurosporine induced activation of caspase 3 activation in human Hela cells assessed as hydrolysis of Z-DEVD-R110 substrate by micropl...More data for this Ligand-Target Pair