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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM10665'
Target
Caspase-3
(Homo sapiens (Human))
Merck Frosst Canada
Ligand
BDBM10665
((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[1-(2-methoxyphe...)
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Affinity Data
IC50: 310nM
pH: 7.0 T: 2°C
Assay Description:
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...
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