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Found 3 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM130419'
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130419(US8822505, 21 | US8822505, 23 | US8822505, 24)
Affinity DataIC50:  0.377nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130419(US8822505, 21 | US8822505, 23 | US8822505, 24)
Affinity DataIC50:  1.04nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130419(US8822505, 21 | US8822505, 23 | US8822505, 24)
Affinity DataIC50:  4.56nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent