Affinity DataIC50: 15nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometryMore data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Inhibition of GCS in GBA mutant human fibroblasts assessed as reduction in glucosylceramide level incubated for 4 days by RapdiFire-MS/MS analysisMore data for this Ligand-Target Pair